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GROUP LEADER

Dr. Aleksander Grabiec

Dr. Aleksander Grabiec

I am a cell biologist with keen interest in epigenetic and transcriptional regulation in chronic inflammatory diseases. My research focuses on understanding how altered expression of epigenetic regulators, transcription factors and signalling molecules contributes to chronic inflammation, and on identification of novel therapeutic strategies targeting these alterations.

I studied biotechnology at the Jagiellonian University in Krakow, Poland, and in 2007 I obtained my MSc degree with specialisation in biochemistry. I performed my doctoral research in the Department Clinical Immunology and Rheumatology, Academic Medical Center, University of Amsterdam, The Netherlands, studying epigenetic and non-epigenetic contributions of histone deacetylases to inflammation in rheumatoid arthritis. In 2012 I received my PhD and then I continued my research on the interplay between epigenetics, transcription factor biology and signal transduction in synovial fibroblasts from patients with inflammatory rheumatic diseases as a postdoctoral researcher.

From 2013 to 2016 I worked as a research associate at the Manchester Collaborative Centre for Inflammation Research (MCCIR), University of Manchester, UK, where I studied the contributions of defective apoptotic cell removal by airway macrophages to the pathology of acute and chronic lung inflammation.

Since October 2016 I work as a Marie Skłodowska-Curie Fellow at the Department of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University in Krakow, Poland. I received a grant from the National Science Centre, Poland, entitled: "Epigenetics of periodontitis: alterations in the host protein acetylation system as a potentially fundamental mechanism for disease development."

Links

 https://www.researchgate.net/profile/Aleksander_Grabiec

https://scholar.google.com/citations?user=ah34KMwAAAAJ&hl=en